• La Tunisie médicale · Oct 2005

    Case Reports

    [Successful use of levosimendan in a patient with cardiogenic shock complicating acute myocardial infarction].

    • Ferjani Mustapha, Hamdi Moufida, Barakette Nedia, Lebbi Anis, Labbene Iheb, and Haouala Habib.
    • Service d'anesthésie réanimeation, Hôpital militaire principal d'instruction de Tunis.
    • Tunis Med. 2005 Oct 1;83(10):635-7.

    AbstractLevosimendan is a new inodilator that improves cardiac contractility by sensitizing troponin C to calcium. This drug has proved to be effective in treating advanced congestive heart failure but has not been evaluated in cardiogenic shock. We present the case of a 54-year-old male patient treated successfully with levosimendan for cardiogenic shock following acute myocardial infarction. Treatment with dobulamine. revascularisation and itra-aortic balloon conterpulsation had first failed to improve his hemodynamic variables. Levosimendan induced a steady decline of increased pulmonary capillary wedge pressure, followed by an increase in cardiac index and mixed venous oxygen saturation. Left ventricular ejection fraction improved from 25% to 47%. Infusion of levosimendan can be used in cardiogenic shock without side effects and to improve hemodynamics and left ventricular function.

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