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Paediatric anaesthesia · May 2001
Randomized Controlled Trial Comparative Study Clinical TrialA prospective randomized controlled study of the efficacy of ketamine for postoperative pain relief in children after adenotonsillectomy.
- R L Aspinall and A Mayor.
- Anaesthetic Department, Royal United Hospital, Bath, UK.
- Paediatr Anaesth. 2001 May 1;11(3):333-6.
BackgroundAdenotonsillectomy is commonly needed by children with obstructive sleep apnoea syndrome. This population is at high risk of life threatening airway obstruction in the postoperative period.MethodsFifty children were studied to test the efficacy of an alternative analgesic to the use of opioids in providing analgesia in the immediate postoperative period. Patients were randomized to receive either 0.1 mg.kg-1 morphine or 0.5 mg.kg-1 ketamine at induction.ResultsKetamine was as effective as morphine with no additional side-effects.ConclusionsKetamine is a safe and effective alternative to morphine to provide analgesia in the immediate postoperative period after tonsillectomy.
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