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Randomized Controlled Trial Comparative Study Clinical Trial
Parturient-controlled epidural analgesia during labour: bupivacaine vs. ropivacaine.
- N P Chua, A T Sia, and C E Ocampo.
- Department of Anaesthesia, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore 229 899.
- Anaesthesia. 2001 Dec 1;56(12):1169-73.
AbstractIn this randomised, controlled study, we compared the hourly dose requirement of ropivacaine 0.125% (group R, n = 16) with bupivacaine 0.125% (group B, n = 16) provided by demand-only (bolus 5 ml, lockout 10 min) parturient-controlled epidural analgesia during labour. The hourly dose requirement was comparable although group R had a lower successful to total demands ratio (p < 0.05). We also found that both groups were clinically indistinguishable in terms of pain relief and side-effects. No difference in maternal or fetal outcome was detected. We conclude that, at a concentration of 0.125%, ropivacaine and bupivacaine were equally effective when self-administered using this patient-controlled regimen.
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