• G A Orliaguet, P A Carli, A Rozenberg, D Janniere, P Sauval, and P Delpech.
• Service d'Aide Médicale Urgente (SAMU) de Paris, Department of Anesthesiology, Hôpital Necker.
• Ann Emerg Med. 1995 Jan 1;25(1):48-51.

Study ObjectivesTo compare the maximal end-tidal carbon dioxide pressure (ETCO2 peak) values obtained during standard (S-CPR) and active compression-decompression CPR (ACD-CPR) during prolonged resuscitation in out-of-hospital cardiac arrest.DesignProspective, randomized crossover study.SettingCity with a population of 3.5 million, served by an emergency medical service system providing advanced cardiac life support.ParticipantsPatients with nontraumatic out-of-hospital cardiac arrest.InterventionsPatients were randomly assigned to receive first, for a period of 3 minutes, either ACD-CPR or S-CPR; then the two methods were alternated. ETCO2 was continuously monitored and computed.Measurements And ResultsSixteen patients (48 +/- 20 years old) were included; in 12, return of spontaneous circulation was achieved, and 5 were admitted alive to the hospital. A statistically significant increase in ETCO2 peak was obtained with ACD-CPR (27.6 +/- 3 mm Hg) compared with S-CPR (15.6 +/- 2.2 mm Hg). No major adverse effect possibly related to ACD-CPR was observed.ConclusionThis prospective study suggests that ACD-CPR may improve cardiac output compared with S-CPR.

16 keywords...

hide…