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Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi · Feb 2013
Review[Research progress of decellularized matrix in tissue engineered trachea transplantation].
- Fangbiao Zhang, Weidong Zhang, and Hongcan Shi.
- Department of General Thoracic Surgery, Medical College of Yangzhou University, Yangzhou Jiangsu, 225001, P.R.China.
- Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2013 Feb 1;27(2):223-6.
ObjectiveTo summarize the recent research situation and progress of decellularized matrix in tissue engineered trachea transplantation and to forecast the possible perspects.MethodsRecent original articles about study and application for decellularized matrix in tissue engineered trachea were reviewed. The application and study of different decellularized matrices involved in animals or patients with tracheal lesions were elaborated.ResultsDecellularized matrices researched and applied in tissue engineered trachea include jejunum, urinary bladder, aorta, and trachea.ConclusionDecellularized urinary bladder matrix and jejunal matrix appears to be efficacious method for the patch repair of partial circumferential tracheal defects. The application of decellularized aortic matrix may need more study, and decellularized tracheal matrix has a bright future in long tracheal defects.
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