• Scand. J. Infect. Dis. · Jan 1996

    Case Reports

    Cerebrospinal fluid filtration in a case of severe pneumococcal meningitis.

    • M Brizzi, A Thorén, and B Hindfelt.
    • Department of Neurology, Malmö University Hospital, Sweden.
    • Scand. J. Infect. Dis. 1996 Jan 1;28(5):455-8.

    AbstractCurrent therapy of bacterial meningitis includes high doses of antibiotics and, sometimes, addition of corticosteroids in order to reduce a harmful inflammatory response. The persisting high mortality and rate of sequelae, particularly regarding pneumococcal meningitis, calls for new therapeutic approaches. We report a case of a 71-year-old female with a pneumococcal meningitis treated with extra-corporeal filtration of cerebrospinal fluid (CSF) after 3 days of coma on conventional treatment. The treatment was carried out without complications and the clinical outcome was favourable. We suggest that filtration of the CSF should be considered as a tool to eliminate noxious substances playing a harmful role in deteriorating course of bacterial meningitis.

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