• Jpn. J. Infect. Dis. · Apr 2003

    Case Reports

    A botulism case of a 12-year-old girl caused by intestinal colonization of Clostridium botulinum type Ab.

    • Hiroshi Kobayashi, Kohji Fujisawa, Yoshihiro Saito, Makoto Kamijo, Sakiko Oshima, Masakatsu Kubo, Yoshikatsu Eto, Chie Monma, and Masaru Kitamura.
    • Department of Pediatrics, Jikei University School of Medicine, Kashiwa Hospital, Chiba 277-0004, Japan.
    • Jpn. J. Infect. Dis. 2003 Apr 1;56(2):73-4.

    AbstractWe encountered a 12-year-old girl, who had contracted food-borne botulism, and subsequently suffered from obstinate constipation for more than half a year. Even on hospital day 122, Clostridium botulinum and its toxin were detected in her stool specimens. The potency of the toxin of the blood serum sampled before treatment was 20 mouse minimum lethal dose per ml. The toxin in the blood had a molecular size equivalent to that of type A botulinum neurotoxin. On hospital day 250, the patient's serum detoxified type A neurotoxin. We confirmed that the patient had food-borne botulism caused by C. botulinum type Ab, followed by intestinal colonization-type botulism.

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