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Ugeskrift for laeger · May 2011
Review[Etomidate can not be recommended to patients with septic shock].
- Palle Toft and Anders Gadegaard Jensen.
- Anæstesiologisk-intensiv Afdeling V, Odense Universitetshospital, 5000 Odense C, Denmark. palle.toft@ouh.regionsyddanmark.dk
- Ugeskr. Laeg. 2011 May 16;173(20):1421-3.
AbstractDue to a low cardiovascular complication rate even in patients with shock, etomidate is often used for intubation. Etomidate inhibits the steroid synthesis. A single bolus injection of etomidate has so far been considered to be safe. However, new investigations have shown that even a single bolus dose of etomidate inhibits the steroid synthesis and is associated with increased mortality in patients with septic shock.
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