• Ann. Allergy Asthma Immunol. · Jan 2002

    Case Reports

    Hair glue anaphylaxis: a hidden latex allergy.

    • Frederick C Cogen and Donald H Beezhold.
    • Laboratory of Immunobiology, Guthrie Research Institute, Sayre, Pennsylvania, USA. AllergyandAsthmaCare@HotMail.com
    • Ann. Allergy Asthma Immunol. 2002 Jan 1;88(1):61-3.

    BackgroundIncreasingly popular cosmetic hair alterations use latex-containing bonding glue to attach hair to the scalp. Immunoglobulin E-mediated reactions to natural rubber latex may occur from unappreciated sources.ObjectiveEvaluation of a case of bonding glue anaphylaxis with immunochemical characterization of the glue.Methods And ResultsA 37-year-old woman developed systemic anaphylaxis upon repeated exposure to hair bonding glue. Skin tests to the glue and latex RAST tests were positive. Her sera reacted to latex antigens including four recombinant Hev b allergens. Assays of the glue revealed antigen patterns resembling ammoniated latex. Antigen levels exceed those reported in other natural rubber latex-dipped products.ConclusionsHair bonding glue contains high concentrations of soluble latex antigen and may cause anaphylaxis without mucosal contact. Repeated glue exposure may potentially sensitize consumers. Physicians, cosmetologists, and latex-allergic patients should be aware of bonding glue-induced immunoglobulin E-mediated reactions associated with hair alterations.

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