• Ear Nose Throat J · Mar 2004

    Case Reports

    Eosinophilic angiocentric fibrosis in a patient with nasal obstruction.

    • Davis B Nguyen, James C Alex, and Benjamin Calhoun.
    • Division of Facial Plastic and Reconstructive Surgery, Section of Otolaryngology, Yale University School of Medicine, New Haven, Conn 06520, USA. davisbnguyen@aol.com
    • Ear Nose Throat J. 2004 Mar 1;83(3):183-4, 186.

    AbstractEosinophilic angiocentric fibrosis (EAF) is a rare clinicopathologic entity that usually affects the upper respiratory tract. We describe the case of a 45-year-old man with nasal obstruction caused by EAF. His lesion featured the distinct radiologic and histopathologic characteristics of EAF, which include an onionskin and whorled fibrosis that surrounds the blood vessels and an inflammatory infiltrate that is predominated by eosinophils. The etiology of EAF remains unknown. Given our increasing knowledge of this rare entity, reports of EAF may appear more frequently in the future.

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