• Anesthesia and analgesia · May 2000

    Review

    Neuromuscular blocking drugs in pediatric patients.

    • B W Brandom.
    • Department of Anesthesiology, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pennsylvania 15213-2583, USA.
    • Anesth. Analg. 2000 May 1;90(5 Suppl):S14-8.

    AbstractThe most useful qualities of a NMBD for pediatric anesthesia are: rapid, reliable onset of laryngeal muscle block after IV or IM administration, duration of < or =20 min, and lack of side effects. Until recently, no nondepolarizer met all these criteria. However, 2 mg/kg rapacuronium produces rapid laryngeal block that can be easily reversed to restore neuromuscular function within 20 min in most pediatric patients.

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