• Kidney international · Sep 2007

    Comment

    Can we do better than a single estimated GFR threshold when screening for chronic kidney disease?

    • E D Poggio and A D Rule.
    • Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA. poggioe@ccf.org
    • Kidney Int. 2007 Sep 1;72(5):534-6.

    AbstractThe Modification of Diet in Renal Disease (MDRD) equation has been used to screen for and diagnose chronic kidney disease (CKD). A fixed estimated glomerular filtration rate cutoff point has been advocated by the National Kidney Foundation to diagnose CKD. However, data derived from healthy individuals challenge this approach and suggest that age- and gender-specific reference values may be more useful in the screening setting.

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