• A B P Donaldson.
• Department of Anaesthesia, Royal Brisbane and Women's Hospital, Brisbane, Queensland.
• Anaesth Intensive Care. 2005 Dec 1;33(6):744-8.

AbstractAdministration of 80% intraoperative oxygen has been proposed as being a cheap, safe and effective means of reducing postoperative nausea and vomiting (PONV) but no studies have been performed in the high risk paediatric population. We tested whether 80% intraoperative oxygen reduces PONV in well children undergoing elective day-stay dental treatment under general anaesthesia. Ninety-five children received standardized sevoflurane, morphine, vecuronium anaesthesia with either 30% or 80% intraoperative oxygen and no antiemetic prophylaxis in a randomized, double blind, prospective trial. There was no difference in PONV or in the use of rescue ondansetron between the groups. The total incidence of PONV was 40% in the group that received 30% oxygen and 33% in those that received 80% oxygen. High inspired intraoperative oxygen was not found to significantly reduce PONV in well children undergoing dental work under general anaesthesia.

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