• James R Bedford and Clare L Ivermee.
• Royal Adelaide Hospital, Adelaide, SA, Australia. jamesbedford@doctors.org.uk
• Crit Care Resusc. 2011 Dec 1;13(4):226-31.

ObjectiveTo determine functional outcomes 6 months after intensive care unit admission for severe infection due to pandemic (H1N1) 2009 influenza and examine the relationship between nutrition during ICU admission and outcome.Design, Setting And ParticipantsRetrospective cohort study of patients with confirmed H1N1 influenza admitted to the ICU, Royal Adelaide Hospital, South Australia, June- October 2009.Main Outcome MeasuresData were collected from medical records, dietitian notes and the daily ICU chart and included: demographics, daily kilocalories (Kcal) and protein delivered compared with dietitian-calculated requirement, ICU and hospital length of stay. Weight change and functional outcome at 6 months were determined prospectively by telephone interview using the 12-Item Short Form Health Survey and the EuroQol Group 5-Dimension Questionnaire.ResultsOf 25 patients with H1N1 infection, 23 were included in the study (14 men; median age, 48 years (interquartile range [IQR], 39-55 years); median Acute Physiology and Chronic Health Evaluation (APACHE) II score, 17 (IQR, 13-21); median ICU length of stay, 9 days (IQR, 4-15 days); median hospital length of stay, 20 days (IQR, 11-30 days); ICU mortality, 3 (13%; 95% CI, 4%- 33%). Enteral feeding was commenced in 16 patients, who received a mean of 71% (SD, 27%; 95% CI, 57%-86%) of their energy and 62% (SD, 25%; 95% CI, 49%-75%) of their protein goals over their ICU stay. A more negative protein balance was associated with prolonged ICU stay (r = - 0.746; P = 0.003). Reduced success of feeding was associated with increased severity of illness and shorter ICU length of stay. Patients reported a good functional outcome at 6 months.ConclusionsPatients admitted to this ICU with H1N1 infection were fed successfully during their stay. Critically ill patients surviving H1N1 infection had good functional outcomes at 6 months.

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