• Critical care clinics · Jan 2016

    Review

    Renal Failure in Pregnancy.

    • Ari Balofsky and Maksim Fedarau.
    • Department of Anesthesiology, University of Rochester Medical Center, 601 Elmwood, Box 604, Rochester, NY 14642, USA.
    • Crit Care Clin. 2016 Jan 1; 32 (1): 73-83.

    AbstractRenal failure during pregnancy affects both mother and fetus, and may be related to preexisting disease or develop secondary to diseases of pregnancy. Causes include hypovolemia, sepsis, shock, preeclampsia, thrombotic microangiopathies, and renal obstruction. Treatment focuses on supportive measures, while pharmacologic treatment is viewed as second-line therapy, and is more useful in mitigating harmful effects than treating the underlying cause. When supportive measures and pharmacotherapy prove inadequate, dialysis may be required, with the goal being to prolong pregnancy until delivery is feasible. Outcomes and recommendations depend primarily on the underlying cause.Copyright © 2016 Elsevier Inc. All rights reserved.

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