• Kristina S Walick, John E Kragh, John A Ward, and John J Crawford.
• Department of Orthopaedics and Rehabilitation, Brooke Army Medical Center, TX, USA. Kristina.walick@amedd.army.mil
• Spine. 2007 Nov 1;32(23):2591-5.

Study DesignParallel group design.ObjectiveCompare the intraocular pressure responses in the prone flat versus prone Trendelenburg's position.Summary Of Background DataPostoperative vision loss (PVL) complicates approximately 0.05% of spine surgeries. Prone positioning is considered a risk factor because it increases intraocular pressure, which may decrease perfusion pressure to the optic nerve (perfusion pressure = mean arterial pressure - intraocular pressure [IOP]). The prone Trendelenburg's position is often used during spine surgery; however, its effect on optic nerve perfusion is unknown. The purpose of this study is to compare the IOP responses in the prone flat versus prone Trendelenburg's positions to determine if prone Trendelenburg's position also risks PVL.MethodsTwenty subjects randomized into 2 groups. Group 1 lay in the prone flat position (0 degrees). Group 2 lay in the prone Trendelenburg's position (-7 degrees). IOPs were measured with a hand-held applanation tonometer while seated, 1 minute after assuming the group's position (Time 0), and at 10-minute intervals for 60 minutes.ResultsThe differences in mean IOPs with respect to positions and time were significant (P = 0.0001, P = 0.000). There was a significant difference between sitting and all other times for both groups. In Group 1, there was a significant difference in IOP between Time 0 and all other times prone flat (P < 0.05). In Group 2, there was a significant difference in IOP between Time 0 all other times prone Trendelenburg (P < 0.05).ConclusionIOP increases in the prone Trendelenburg's position, and when combined with other factors, may be a risk factor for PVL. The pathophysiology is discussed and suggestions for clinicians are made.

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