• Thierry Le Tourneau, Mohamad Betto, Marjorie Richardson, Francis Juthier, Pierre Vladimir Ennezat, Anne-Sophie Polge, Christophe Bauters, André Vincentelli, and Ghislaine Deklunder.
• Int. J. Cardiol. 2010 Nov 19;145(2):319-20.

AbstractMultiple cardiac papillary fibroelastomas (PFEs) are thought to account for less than 10% of patients with PFE. We aimed at evaluating the frequency and location of multiple PFEs and the reliability of transthoracic (TTE) and transoesophageal (TEE) echocardiography in diagnosing multiple PFEs. Twenty-six consecutive patients (52±14 years, 65% males) with pathologically confirmed PFE had 21 PFEs diagnosed by TTE, 33 by TEE, and 62 at surgery. Eight patients (31%) had multiple PFEs found either by TEE or at surgery. Aortic valve was involved in 75% of patients with multiple PFEs and left ventricle in 38% of patients. The sensitivity of TTE in diagnosing any PFEs was 51.3% and 76.9% for TEE. Our study emphasizes the high frequency of multiple PFEs, the need of TEE for all presumed PFE and the need for careful assessment of left-sided endocardial surfaces, especially of the aortic valve, during PFE excision.Copyright © 2009 Elsevier Ireland Ltd. All rights reserved.

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