• Pediatr. Nephrol. · Dec 1997

    Clinical Trial

    Continuous veno-venous hemodiafiltration using bicarbonate dialysate.

    • D Roy, R J Hogg, P A Wilby, N Matthews, P H Henning, and K F Jureidini.
    • Department of Nephrology, Women's and Children's Hospital, North Adelaide, South Australia.
    • Pediatr. Nephrol. 1997 Dec 1;11(6):680-3.

    AbstractWe report our experience with 11 children treated by continuous veno-venous hemodiafiltration. The median age was 5.0 years (range 3 days to 14 years). Access was via dual-lumen subclavian or femoral vein catheters. Hemofilters were chosen on the basis of patient size and dialysis requirements. Bicarbonate-buffered dialysis solution was prepared shortly before use by supplementation of a specially prepared base solution with commercially available electrolyte solutions. The mean ultrafiltration rate was 37.4 +/- 27 ml/kg body weight per hour. Urea and creatinine clearances were 15.1 +/- 6.4 ml/kg body weight per min and 16.4 +/- 8.4 ml/kg body weight per min, respectively. Metabolic acidosis was readily controlled in all patients. Of the 11 patients, 7 ultimately recovered normal renal function.

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