• Br J Anaesth · Apr 1992

    Randomized Controlled Trial Comparative Study Clinical Trial

    Recovery from day-case anaesthesia: comparison of total i.v. anaesthesia using propofol with an inhalation technique.

    • J J Nightingale and I H Lewis.
    • Shackleton Department of Anaesthetics, Southampton General Hospital, Hants.
    • Br J Anaesth. 1992 Apr 1;68(4):356-9.

    AbstractA prospective, double-blind study was conducted to compare postoperative recovery after either total i.v. anaesthesia (TIVA: propofol and alfentanil) or an inhalation technique (propofol and alfentanil followed by nitrous oxide and isoflurane) in 50 patients undergoing day-case gynaecological surgery. Psychomotor performance was assessed at 1 and 2 h after surgery using the Critical Flicker Fusion Threshold (CFFT), Simple Reaction Time (SRT) and Choice Reaction Time (CRT). Subjective recovery and side effects after discharge from hospital were assessed using a postal questionnaire. Recovery occurred significantly earlier in the TIVA group as assessed by CFFT and SRT (P less than 0.01); there were no significant differences (P greater than 0.05) between the two groups in CRT, subjective duration of recovery or side effects.

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