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- Hatem A Azim, Fedro A Peccatori, Sarah J Liptrott, Chiara Catania, and Aron Goldhirsch.
- Department of Medicine, European Institute of Oncology, Via Ripamonti 435, Milan, Italy.
- Nat Rev Clin Oncol. 2009 Jun 1;6(6):367-70.
BackgroundA 29-year-old woman was diagnosed with lymph-node-positive, steroid-hormone-receptor-negative and HER2/neu-positive breast cancer. She underwent surgery followed by cyclophosphamide, epirubicin, and 5-fluorouracil chemotherapy, and received radiotherapy followed by trastuzumab therapy for 1 year. During the tenth month of trastuzumab therapy, the patient reported a missed period and had a positive pregnancy test.InvestigationsPhysical examination, pregnancy test, echocardiography.DiagnosisUnintended pregnancy during adjuvant trastuzumab therapy.ManagementCessation of trastuzumab and close monitoring of mother and fetus during pregnancy.
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