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- Dharshi Karalapillai, Melissa Kaufman, and Laurence Weinberg.
- Austin Health, Melbourne, VIC, Australia. dharshi.karalapillai@austin.org.au
- Crit Care Resusc. 2013 Mar 1;15(1):57-62.
AbstractSugammadex is the first selective antagonist to reverse neuromuscular blockade induced by rocuronium and vecuronium. The mechanism by which sugammadex works is superior to current neuromuscular block reversal strategies in terms of speed, efficacy and side effects. There is little contemporary guidance on the use of sugammadex in intensive care medicine. This review covers the key pharmacological features, clinical uses and cost- effectiveness in the context of intensive care practice.
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