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Comparative Study
Relation of chronic and acute glycemic control on mortality in acute myocardial infarction with diabetes mellitus.
- Jie J Cao, Michael Hudson, Michelle Jankowski, Fred Whitehouse, and W Douglas Weaver.
- National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA. caoj@nhlbi.nih.gov
- Am. J. Cardiol. 2005 Jul 15;96(2):183-6.
AbstractAcute hyperglycemia during myocardial infarction predicts adverse short-term outcomes and mortality in diabetic patients. Conversely, chronic hyperglycemia is associated with an increased incidence of long-term cardiovascular complications, although its effect on acute hyperglycemic response and mortality after acute myocardial infarction is unknown. We investigated the prognostic relation of the glucose concentration at admission and the baseline average glycohemoglobin on acute myocardial infarction mortality. Of 808 consecutive diabetic patients with acute myocardial infarction, the most significant independent predictor of in-hospital mortality was the glucose concentration at admission. Baseline glycohemoglobin strongly correlated with admission hyperglycemia but did not predict mortality independently.
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