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Case Reports
Postoperative respiratory depression and unresponsiveness following epidural opiate administration: a case report.
- Johnnie Holmes and John P Maye.
- Naval Hospital, Camp Lejeune, NC, USA.
- AANA J. 2004 Apr 1;72(2):126-8.
AbstractThe profound segmental antinociception that epidural opioids offer has increased their use over the last 2 decades. Though side effects may accompany the use of epidural opioids, clinicians have found that the advantages far outweigh the disadvantages. The following case report outlines a patient's postoperative course in which she experienced respiratory depression while receiving epidural opioids. The pharmacokinetics of lipophilic vs hydrophilic opioids in relation to the occurrence of respiratory depression is discussed.
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