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Rheum. Dis. Clin. North Am. · May 2011
ReviewMetabolic myopathies: clinical features and diagnostic approach.
- Edward C Smith, Areeg El-Gharbawy, and Dwight D Koeberl.
- Division of Pediatric Neurology, Department of Pediatrics, Duke University Medical Center, DUMC Box 3936, Durham, NC 27710, USA.
- Rheum. Dis. Clin. North Am. 2011 May 1;37(2):201-17, vi.
AbstractThe rheumatologist is frequently called on to evaluate patients with complaints of myalgia, muscle cramps, and fatigue. The evaluation of these patients presents a diagnostic challenge given the nonspecific and intermittent nature of their complaints, often leading to inappropriate diagnostic testing. When these symptoms are associated with physical exertion, a metabolic myopathy should be suspected Although inflammatory myopathies may present with similar features, such a pattern should prompt a thorough evaluation for an underlying metabolic myopathy. This review discusses the most common causes of metabolic myopathies and reviews the current diagnostic options available to the clinician.Copyright © 2011 Elsevier Inc. All rights reserved.
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