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- Ashley N Fricks-Gleason, Anna J Khalaj, and John F Marshall.
- University of California, Irvine. Department of Neurobiology & Behavior, 2205 McGaugh Hall, Irvine, CA 92697-4550, USA.
- Behav. Brain Res. 2012 Jan 1;226(1):357-60.
AbstractIncreasingly, research suggests a role for dopamine D1 receptors in the consolidation of extinction of both appetitive and aversive memories. However, a role for D1 receptors in extinction of memories involving drug reward has yet to be established. Here we show that post-retrieval, but not delayed, systemic administration of the D1 receptor antagonist SCH23390 results in prolonged extinction of cocaine conditioned place preference (CPP), suggesting a critical role for D1 receptors in the consolidation of extinction of cocaine-cue memories.Copyright © 2011 Elsevier B.V. All rights reserved.
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