• Internal medicine · Jan 2008

    Review Case Reports

    Meningococcemia without meningitis in Japan.

    • Tetsuya Horino, Tetsuro Kato, Fumiya Sato, Mitsuo Sakamoto, Yasushi Nakazawa, Masaki Yoshida, Shoichi Onodera, Masato Kohda, Koma Matsuo, Takaoki Ishiji, Hideyuki Takahashi, and Haruo Watanabe.
    • Department of Infectious Disease and Infection Control, The Jikei University School of Medicine. horino@jikei.ac.jp
    • Intern. Med. 2008 Jan 1;47(17):1543-7.

    AbstractWe report a case of meningococcemia without meningitis, which is a rare infectious disease in Japan. A 32-year-old woman was referred to our hospital with fever and joint pain. Her clinical presentation and the results of laboratory examination on admission suggested viral infection. However, her condition rapidly progressed to septic shock with fulminans purpura. Blood culture grew Neisseria meningitidis. She received antimicrobial therapy and underwent localized therapy for skin lesions. Meningococcal infection should be considered in patients who have fever along with skin rash or petechiae even when there are no signs of meningitis. In this report, we also review case reports of meningococcemia without meningitis in Japan.

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