• Am. J. Crit. Care · Nov 2012

    Case Reports

    Dexmedetomidine to treat lisdexamfetamine overdose and serotonin toxidrome in a 6-year-old girl.

    • Olugbenga A Akingbola and Dinesh Singh.
    • Department of Pediatrics at Tulane Hospital for Children, New Orleans, Louisiana 70112-2632, USA. oakingbo@tulane.edu
    • Am. J. Crit. Care. 2012 Nov 1;21(6):456-9.

    AbstractA 6-year-old girl displayed symptoms of serotonin syndrome after accidental ingestion of Vyvanse (lisdexamfetamine dimesylate). Dexmedetomidine was administered because of persistent neuromuscular hyperactivity and severe agitation despite initial therapy with benzodiazepines. Some children show a paradoxical reaction to benzodiazepines, and dexmedetomidine has a possible role in the treatment of serotonin syndrome.

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