• Zhonghua yi xue za zhi · Feb 2003

    Meta Analysis

    [A meta-analysis of clinical studies of low volume ventilation in acute respiratory distress syndrome].

    • Zhi-qiang Qin and Chen Wang.
    • Beijing Institute of Respiratory Medicine, Beijing Chaoyang Hospital-Affiliate of Capital University of Medical Sciences, Beijing 100020, China.
    • Zhonghua Yi Xue Za Zhi. 2003 Feb 10;83(3):224-7.

    ObjectivePool the published data of randomized-controlled trials (RCTs) about the effect of low volume ventilation in acute respiratory distress syndrome (ARDS) and evaluate if low volume ventilation can reduce the mortality of ARDS.MethodsMEDLINE and CBM discs from 1991 to 2001 were selected for the data sources. The inclusion criteria were: the subjects were patients with ARDS, the study lasted 10 days or more and was RCT, the mortality of ARDS in low volume ventilation group was compared with that in traditional ventilation group. The data of the studies included were processed with a meta-analysis.Results1,435 cases in 7 studies were included, 5 of 7 studies did not show significant different mortalities between the two treatment groups and 2 studies indicated the low volume ventilation could improved the survival of ARDS. The mortalities of ARDS in low tidal volume ventilation group and traditional ventilation group were 35.98% (258/717) and 42.62% (306/718) respectively. The combined OR of all studies was 0.754 (95% CI 0.610 - 0.933), P < 0.01.ConclusionLow volume ventilation benefits the survival of ARDS. It is worth application in clinical practice.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…