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Se Asian J Trop Med · Mar 2000
Case ReportsImipenem therapy for septicemic melioidosis in a child with penicillin and cephalosporin adverse reaction.
- P Lumbiganon and O Panamonta.
- Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Thailand.
- Se Asian J Trop Med. 2000 Mar 1;31(1):89-90.
AbstractThe recommended treatment for severe melioidosis is ceftazidime or a combination of ceftazidime and trimethoprim-sulfamethoxazole (TMP/SMX). Amoxicillin-clavulanate has been shown to be an effective alternative therapy. In patient who is allergic to penicillin and cephalosporin, imipenem an alternative drug may be used. We described a 10 year-old boy who was diagnosed as septicemic melioidosis and type 1 diabetes mellitus. He developed fever and rash while being given ceftazidime and TMP/SMX. The fever recurred when amoxicillin-clavulanate was administered orally. He was successfully treated with imipenem.
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