• Paediatric anaesthesia · Sep 2002

    Randomized Controlled Trial Clinical Trial

    Analgesia for paediatric tonsillectomy and adenoidectomy with intramuscular clonidine.

    • Katherine O Freeman, Neil Roy Connelly, Donald Schwartz, Barry R Jacobs, Jerry M Schreibstein, and Charles Gibson.
    • Department of Anesthesiology, Baystate Medical Center, Springfield, MA 01199, USA.
    • Paediatr Anaesth. 2002 Sep 1;12(7):617-20.

    BackgroundAfter undergoing tonsillectomy and adenoidectomy (T&A), children may experience significant pain. Clonidine, an alpha2 agonist, exhibits significant analgesic properties. The current investigation sought to determine whether intramuscular (I.M.) clonidine would decrease pain in paediatric patients undergoing T&A.MethodsThirty-nine children undergoing elective T&A were studied. Following inhalational anaesthetic induction, fentanyl (2 microg x kg(-1)) was given intravenously, acetaminophen (paracetamol) (30 mg.kg-1) was given rectally and the children then randomly received an i.m. injection of either normal saline or clonidine (2 microg x kg(-1)). Perioperative analgesic requirements in the postanaesthesia care unit and at home following hospital discharge were evaluated.ResultsThere were no significant demographic, analgesic consumption, haemodynamic or pain score differences between the groups.ConclusionsWe do not recommend adding i.m. clonidine (2 microg x kg(-1)) to the analgesic regimen of children undergoing tonsillectomy and adenoidectomy.

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