-
Randomized Controlled Trial Multicenter Study
Preoperative MR Imaging in Patients with Intermittent Neurogenic Claudication: Relevance for Diagnosis and Prognosis.
- Wouter A Moojen, Catharina D Schenck, Lycklama À Nijeholt Geert J GJ Department of Radiology, Medical Center Haaglanden, The Hague, The Netherlands., Jacobs Wilco C H WCH Department of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands., Bas F Van der Kallen, Mark P Arts, Wilco C Peul, Vleggeert-Lankamp Carmen L A M CLAM Department of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands., and Leiden-The Hague Spine Intervention Prognostic Study Group (SIPS).
- Department of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands.
- Spine. 2018 Mar 1; 43 (5): 348-355.
Study DesignWe studied baseline magnetic resonance images of 155 patients with intermittent neurogenic claudication and lumbar spinal stenosis (LSS). Magnetic resonance imaging (MRI) and patient data were gathered from participants of a randomized trial.ObjectiveIt is believed that the narrowness of the lumbar spinal canal correlates to the severity of complaints and that it may be a good predictor of clinical outcome if treated. However, this hypothesis has never been (prospectively) tested.Summary Of Background DataMRI is an important tool to confirm the diagnosis of LSS as a cause for intermittent neurogenic claudication.MethodsThree raters were asked to evaluate the magnetic resonance images (Schizas scale). Symptom severities at baseline and 1-year follow-up were quantified. The radiological scores were correlated with clinical baseline and outcome scores to assess diagnostic and prognostic value of MRI findings at baseline.ResultsThere was good agreement on the clinically relevant level of LSS (kappa range 0.57-0.64). MRI assessment of grading of compression (kappa 0.33-0.46) did not correlate with baseline MRDQ nor with outcome based on postoperative change in MRDQ (P = 0.61). However, both absence of epidural fat and presence of tortuous caudal nerves on magnetic resonance images (kappa 0.53-0.72 and 0.67-0.70) in patients with LSS were relatively good predictors for satisfactory recovery after surgery (P = 0.03 and P < 0.01).ConclusionThe grading of compression on the preoperative MRI is neither ambiguous nor correlating to severity of clinical condition. It does, furthermore, not have the ability to predict the outcome after 1 year if surgically treated.Level Of Evidence2.
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