• Clinics in chest medicine · Sep 2010

    Review

    Pulmonary manifestations of the idiopathic inflammatory myopathies.

    • Meena Kalluri and Chester V Oddis.
    • Division of Pulmonary Medicine, University of Alberta, Edmonton, Canada. meenakalluri@med.ualberta.ca
    • Clin. Chest Med. 2010 Sep 1;31(3):501-12.

    AbstractPulmonary involvement in myositis includes interstitial lung disease (ILD), respiratory muscle weakness, aspiration, infections, and drug-induced disease. ILD may precede myositis, and results in increased morbidity and mortality rates. Initial evaluation should include pulmonary function tests and high-resolution computed tomography. Nonspecific interstitial pneumonia (NSIP) is the most common histologic pattern on lung biopsy. Treatment usually consists of a combination of steroids and other immunosuppressive agents, and the response depends on the clinical presentation and underlying histology.

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