• Critical care nurse · Apr 2012

    Central neurogenic diabetes insipidus, syndrome of inappropriate secretion of antidiuretic hormone, and cerebral salt-wasting syndrome in traumatic brain injury.

    • Cynthia A John and Michael W Day.
    • Providence Sacred Heart Medical Center and Children’s Hospital, Spokane, Washington 99216, USA. cnsd_ccrn@yahoo.com
    • Crit Care Nurse. 2012 Apr 1;32(2):e1-7; quiz e8.

    AbstractCentral neurogenic diabetes insipidus, syndrome of inappropriate secretion of antidiuretic hormone, and cerebral salt-wasting syndrome are secondary events that affect patients with traumatic brain injury. All 3 syndromes affect both sodium and water balance; however, they have differences in pathophysiology, diagnosis, and treatment. Differentiating between hypernatremia (central neurogenic diabetes insipidus) and the 2 hyponatremia syndromes (syndrome of inappropriate secretion of antidiuretic hormone, and cerebral salt-wasting syndrome) is critical for preventing worsening neurological outcomes in patients with head injuries.

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