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Critical care nurse · Feb 2013
Case ReportsAcute liver failure in an obstetric patient: challenge of critical care for 1 patient with 2 subspecialty needs.
- Holly Castello, Lisa Schoch, and Tracy A Grogan.
- University of Pittsburgh Medical Center, Pittsburgh, PA, USA. castha@upmc.edu
- Crit Care Nurse. 2013 Feb 1;33(1):48-56.
AbstractAcute fatty liver of pregnancy is a rare and life-threatening disease associated with a defect in fatty acid metabolism in the fetus that causes liver disease in the mother. Prompt diagnosis and management are critical to the outcome of both the mother and the fetus and require involvement of several medical specialties, including hepatology, obstetrics, and, possibly, critical care. The included case study describes a woman with acute fatty liver of pregnancy decompensating to acute liver failure complicated by encephalopathy, cerebral edema, and intracranial hypertension. Subsequent management of these conditions, including the woman's progression to liver transplant, is provided.
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