• Am J. Orthop. · Oct 2007

    Randomized Controlled Trial

    Effects of a preoperative femoral nerve block on pain management and rehabilitation after total knee arthroplasty.

    • Robert P Good, Michael H Snedden, Frank C Schieber, and Andrea Polachek.
    • Bryn Mawr Hospital, Bryn Mawr, PA 19010, USA. rpg@orthspec.com
    • Am J. Orthop. 2007 Oct 1;36(10):554-7.

    AbstractThe objective of this prospective, randomized, double-blind study was to determine if preoperative administration of a femoral nerve block reduces the amount of morphine needed for postoperative analgesia after total knee arthroplasty (TKA). Forty-two patients undergoing TKA were randomly assigned to receive either a femoral nerve block (0.50% bupivacaine hydrochloride with epinephrine 1:200,000) or matching placebo. Results showed postoperative morphine use was significantly lower in patients who received the nerve block (25.5 vs 37.5 mg, P = .016); however, the 2 groups had similar pain scores and rehabilitative outcomes. In general, a preoperative femoral nerve block is a safe and effective adjunct for decreasing morphine use for post-TKA analgesia.

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