• Stereotact Funct Neurosurg · Jan 2008

    Case Reports

    Low-frequency bilateral hypothalamic stimulation for treatment of drug-resistant aggressiveness in a young man with mental retardation.

    • Virgilio Hernando, Jesus Pastor, Manuel Pedrosa, Esteban Peña, and R G Sola.
    • Functional Neurosurgery Unit, Hospital Universitario La Princesa, Madrid, Spain. vhrequejo@hotmail.com
    • Stereotact Funct Neurosurg. 2008 Jan 1;86(4):219-23.

    AbstractStereotactic bilateral electrode implantation in the medial portion of the posterior hypothalamus was performed on a 22-year-old male with drug-resistant aggressiveness. To localize the targets during implantation, microrecording was performed, and the clinical and electroencephalographic responses to intraoperative stimulation were monitored. The patient had an improved response to low-frequency stimulation that was sustained 18 months later at a follow-up examination.(c) 2008 S. Karger AG, Basel

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