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- Y Alkan, W E Haefeli, J Burhenne, J Stein, I Yaniv, and I Shalit.
- Infectious Diseases Unit, Schneider Children's Medical Center of Israel, Sackler School of Medicine, Tel-Aviv University, Israel.
- Clin. Infect. Dis. 2004 Sep 15;39(6):e49-52.
AbstractA 15-year-old patient with acute lymphoblastic leukemia and Fusarium infection was treated with voriconazole. She developed asymptomatic bradycardia, QT interval prolongation, and nonsustained, polymorphic ventricular tachycardia, which recurred upon rechallenge with the drug. Voriconazole levels and metabolism were within expected normal values. This non-concentration-dependent, voriconazole-associated ventricular tachycardia mandates cardiac rhythm monitoring during voriconazole treatment.
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