• Cancer Treat. Res. · Jan 2011

    Review

    Thrombocytopenia and platelet transfusions in patients with cancer.

    • Jason Valent and Charles A Schiffer.
    • Division of Hematology/Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA. valentjs@hotmail.com
    • Cancer Treat. Res. 2011 Jan 1;157:251-65.

    AbstractPlatelet transfusions are a critical component of the supportive care for patients receiving intensive therapy for hematologic malignancies. The platelet count "triggering" prophylactic transfusion has decreased over the years, and studies comparing a prophylactic versus a therapeutic transfusion approach are in progress. The evidence supporting the need for platelet transfusions prior to different invasive procedures is reviewed. Lastly, studies evaluating the use of thrombopoietic stimulating agents to reduce hemorrhage and decrease the need for platelet transfusions are discussed. To date, there is no evidence that this approach is of clinical utility.

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