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Clin. Pharmacol. Ther. · Jun 2015
ReviewCannabinoid replacement therapy (CRT): Nabiximols (Sativex) as a novel treatment for cannabis withdrawal.
- D J Allsop, N Lintzeris, J Copeland, A Dunlop, and I S McGregor.
- Psychopharmacology Laboratory, School of Psychology, Faculty of Science, University of Sydney, NSW, Australia.
- Clin. Pharmacol. Ther. 2015 Jun 1;97(6):571-4.
AbstractCannabis is a common recreational drug that is generally considered to have low addictive potential. However, an increasing number of cannabis users are seeking treatment for dependence on the drug. There is interest in using agonist (substitution) pharmacotherapies to treat cannabis dependence and here we outline a novel approach involving a buccal spray (nabiximols) that contains tetrahydrocannabinol (THC) and cannabidiol (CBD). We review recent research with nabiximols and highlight findings relevant to clinical practice.© 2015 American Society for Clinical Pharmacology and Therapeutics.
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