Control of hyperglycaemia in paediatric intensive care (CHiP):

Bmc Pediatr · Jan 2010

Randomized Controlled Trial Comparative Study

Control of hyperglycaemia in paediatric intensive care (CHiP): study protocol.

There is increasing evidence that tight blood glucose (BG) control improves outcomes in critically ill adults. Children show similar hyperglycaemic responses to surgery or critical illness. However it is not known whether tight control will benefit children given maturational differences and different disease spectrum. ⋯ The relevance of tight glycaemic control in this population needs to be assessed formally before being accepted into standard practice.

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- Duncan Macrae, John Pappachan, Richard Grieve, Roger Parslow, Simon Nadel, Margrid Schindler, Paul Baines, Peter-Marc Fortune, Zdenek Slavik, Allan Goldman, Ann Truesdale, Helen Betts, Elizabeth Allen, Claire Snowdon, Deborah Percy, Michael Broadhead, Tara Quick, Mark Peters, Kevin Morris, Robert Tasker, and Diana Elbourne.
- Paediatric Intensive Care Unit, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK. D.macrae@rbht.nhs.uk
- Bmc Pediatr. 2010 Jan 1;10:5.
BackgroundThere is increasing evidence that tight blood glucose (BG) control improves outcomes in critically ill adults. Children show similar hyperglycaemic responses to surgery or critical illness. However it is not known whether tight control will benefit children given maturational differences and different disease spectrum.Methods/DesignThe study is an randomised open trial with two parallel groups to assess whether, for children undergoing intensive care in the UK aged DiscussionThe relevance of tight glycaemic control in this population needs to be assessed formally before being accepted into standard practice.

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Control of hyperglycaemia in paediatric intensive care (CHiP): study protocol.

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