• Chad E Afman, Jeffrey A Welge, and David L Steward.
• Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, Ohio, USA. afmanc@UCMAIL.UC.EDU
• Otolaryngol Head Neck Surg. 2006 Feb 1;134(2):181-6.

ObjectivesTo determine whether meta-analysis supports the use of corticosteroids to reduce post-tonsillectomy pain for pediatric patients.MethodsA systematic review of currently available randomized controlled trials using a single-dose, intravenous corticosteroid during pediatric tonsillectomy was performed. Visual analog pain scale (VAS) data was extracted with reviewers blinded to results. Meta-analysis was performed with weighted mean difference and random-effects model using Revman 4.2 software.ResultsEight randomized trials were included in analysis of post-tonsillectomy pain. A statistically significant reduction in pain as measured by VAS on postoperative day 1 was noted (mean VAS difference = -0.97; CI 95 % = -1.74,-0.19; P = 0.01).ConclusionsA single, intraoperative dose of dexamethasone may reduce post-tonsillectomy pain on postoperative day 1, by a factor of 1 on a 10-point pain scale. As the side effects and cost of dexamethasone dose appear negligible, consideration of routine use seems reasonable.

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