• Intensive care medicine · Jan 1992

    Comparative Study

    A comparison of continuous positive pressure ventilation, combined high frequency ventilation and airway pressure release ventilation on experimental lung injury.

    • I Jousela, K Linko, and A Mäkeläinen.
    • Department of Anaesthesia, Helsinki University Central Hospital, Finland.
    • Intensive Care Med. 1992 Jan 1;18(5):299-303.

    AbstractIn pigs with oleic induced lung injury, the effectiveness of combined high frequency ventilation (CHFV, with VDR-Phasitron) and airway pressure release ventilation (APRV) were compared to continuous positive pressure ventilation (CPPV) in a randomized study. The respiratory rate was 15/min, CPAP 8 mmHg and FiO2 0.25. PaCO2 was maintained at 5 kPa. PaO2 was significantly lower with APRV (12.5 +/- 3.9 kPa, CPPV: 15.8 +/- 3.9 kPa, and CHFV: 15.5 +/- 3.2 kPa). This was in accordance with the lowest peak airway pressure during APRV (20.9 +/- 4.8 mmHg, CPPV: 26.3 +/- 4.4 mmHg and CHFV: 28.2 +/- 3.7 mmHg). There was no difference in the pericardiac pressure between the 3 ventilation modes. The pressure related depressive effects on the cardiovascular function during CHFV and APRV were similar to those during CPPV. Adequate oxygenation and ventilation could be achieved with both CHFV and APRV, but these methods were not superior to CPPV.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        

    hide…

What will the 'Medical Journal of You' look like?

Start your free 21 day trial now.

We guarantee your privacy. Your email address will not be shared.