• Am. J. Surg. · Apr 2011

    The influence of race on the development of acute lung injury in trauma patients.

    • Lisa M Brown, Richard H Kallet, Michael A Matthay, and Rochelle A Dicker.
    • Department of Surgery, University of California, San Francisco at San Francisco, General Hospital, 94143, USA.
    • Am. J. Surg. 2011 Apr 1;201(4):486-91.

    BackgroundAcute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are sequelae of severe trauma. It is unknown if certain races are at greater risk of developing ALI/ARDS, and once established, if there are racial differences in the severity of lung injury or mortality.MethodsRetrospective cohort study of 4,397 trauma patients (1,831 Caucasians, 871 African-Americans, 886 Hispanics, and 809 Asian/Pacific Islanders) requiring intensive care unit (ICU) admission between 1996 and 2007 at an urban Level I trauma center.ResultsAfrican-American patients were most likely to present in shock with penetrating trauma and receive a massive transfusion. The incidence of ALI/ARDS was similar by race (P = .99). Among patients who developed ALI/ARDS, there was no evidence to support a difference in partial pressure of oxygen in arterial blood to fraction of inspired oxygen (Pao(2)/Fio(2)) (P = .33), lung injury score (P = .67), or mortality (P = .78) by race.ConclusionsDespite differences in baseline characteristics, the incidence of ALI/ARDS, severity of lung injury, and mortality were similar by race.Copyright © 2011 Elsevier Inc. All rights reserved.

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