• Neuroscience letters · Feb 2009

    Case Reports

    Oculogyric crisis with exacerbation of psychosis: Possible mechanism and clinical implications.

    • Naveen Thomas, Shyam Sundar Gopi Sankar, Deepa Braganza, and S Jayakrishnan.
    • Department of Psychiatry, Christian Medical College, Bagayam, Vellore 632 002, Tamil Nadu, India. naveenlinda2002@yahoo.co.in
    • Neurosci. Lett. 2009 Feb 13;451(1):50-1.

    AbstractOculogyric crisis is a distressing acute/chronic side effect of neuroleptic medications. Chronic oculogyric crisis can be considered as a tardive hyperkinetic movement disorder and it may be associated with worsening of psychotic symptoms. Treatment strategies for chronic oculogyric crisis include; high potency antipsychotics and anticholinergics drugs for immediate relief and clozapine as a long-term treatment strategy. Here we are presenting case histories of four patients with oculogyric crisis and associated worsening of psychosis, its possible etiology and various treatment strategies.

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