• Postgraduate medicine · May 2011

    Sleep among opioid users.

    • Anil K Paturi, Salim Surani, and Kannan Ramar.
    • Mayo Clinic, Critical Care Medicine, Rochester, MN, USA.
    • Postgrad Med. 2011 May 1;123(3):80-7.

    AbstractUse of opioids in the treatment of both acute and chronic pain has increased significantly in the past 2 decades. Recent literature suggests that chronic opioid use is related to sleep-related breathing disorders, particularly central sleep apnea of both the periodic and nonperiodic breathing pattern. The clinical significance, pathogenesis, and treatment options of these sleep-related breathing disorders are not well understood. This article summarizes the current literature on the effects of both acute and chronic opioid use on sleep, sleep-disordered breathing, and the current evidence on various treatment options for breathing disorders related to chronic opioid use.

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