• Critical care medicine · Nov 1998

    Review Case Reports

    Increased apnea threshold in a pediatric patient with suspected brain death.

    • R Vardis and M M Pollack.
    • Department of Critical Care, Children's National Medical Center, Washington, DC, USA.
    • Crit. Care Med. 1998 Nov 1;26(11):1917-9.

    ObjectiveTo evaluate the current standards for apnea testing in the evaluation of brain death in children.DesignCase report.SettingA tertiary pediatric intensive care unit (ICU).PatientsA single patient admitted to the ICU.InterventionsNone.Measurements And Main ResultsA formal brain death examination was performed on a 4-yr-old male with a diagnosis of acute pilocytic astrocytoma and global cerebral hypoxic ischemic damage secondary to a cardiorespiratory arrest. The patient fulfilled all criteria for brain death, except the apnea test. An apnea test was performed for 9 mins 23 secs, at which time, spontaneous respiratory effort was noted. The respiratory efforts were initiated with a pH of 7.08 and a PaCO2 of 91 torr (12.1 kPa).ConclusionThis case report suggests that current guidelines for apnea testing may lead to erroneous evaluation of medullary-respiratory drive.

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