• Am J Emerg Med · Nov 1999

    Review

    Succinylcholine: adverse effects and alternatives in emergency medicine.

    • S L Orebaugh.
    • Department of Emergency Medicine, University of Pittsburgh Medical Center, Southside, PA 15203, USA.
    • Am J Emerg Med. 1999 Nov 1;17(7):715-21.

    AbstractSuccinylcholine has long been the favored neuromuscular blocking agent for emergent airway management because of its rapid onset, dependable effect, and short duration. However, it has a plethora of undesirable side effects, ranging from the inconsequential to the catastrophic. When patients requiring tracheal intubation present with potential contraindications to succinylcholine use, the emergency physician will need to substitute a rapid-onset nondepolarizing neuromuscular blocking agent, such as rocuronium or mivacurium. An understanding of the pharmacology of these agents is essential.

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