• Masui · May 2008

    Randomized Controlled Trial

    [Optimal dose of fentanyl for postoperative epidural analgesia after thoracic surgery].

    • Akio Yamagishi, Yuichi Asai, and Hiroshi Iwasaki.
    • Department of Anesthesiology, Obihiro National Hospital, Obihiro 080-8518.
    • Masui. 2008 May 1;57(5):610-5.

    BackgroundWe investigated the dose of fentanyl in ropivacaine for epidural anesthesia that will provide effective analgesia with minimal side effects after thoracic surgery.MethodsSixty patients scheduled to undergo thoracic surgery were randomly allocated to four groups according to fentanyl dose in epidural analgesia: group R (0 microg x hr(-1); n = 15), group F1 (5 microg x hr(-1); n = 15), group F2 (10 microg x hr(-1); n = 15) and group F3 (15 microg x hr(-1); n = 15). Pain scores (visual analogue scale: VAS) were assessed at 1, 3, 6, 12, 24, and 48 hrs after surgery. Degrees of satisfaction regarding pain relief and complications during a period of 48 hrs after surgery were compared.ResultsPain scores in group F3 were significantly lower than those in the other groups at 3, 6, and 12 hrs after surgery. The number of postoperative analgesics used in group R was significantly more than the numbers used in other groups. The incidences of side effects were similar in the four groups.ConclusionsWe conclude that continuous epidural administration of more than 15 microg x hr(-1) of fentanyl in ropivacaine provides pain relief and few side effects after thoracic surgery.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…