• J M Añon, V Gómez-Tello, E González-Higueras, V Córcoles, M Quintana, A García de Lorenzo, J J Oñoro, C Martín-Delgado, A García-Fernández, L Marina, F Gordo, G Choperena, R Díaz-Alersi, J C Montejo, and J López-Martínez.
• Servicio de Medicina Intensiva, Hospital Virgen de la Luz, Cuenca, España. jmaelizalde@gmail.com
• Med Intensiva. 2013 Apr 1;37(3):149-55.

ObjectiveTo analyze the prognosis of mechanically ventilated elderly patients in the Intensive Care Unit (ICU).Design And ScopeSub-analysis of a prospective multicenter observational cohort study conducted over a period of two years in 13 medical-surgical ICUs in Spain.PatientsAdult patients who required mechanical ventilation (MV) for longer than 24 hours.InterventionsNone.Study VariablesDemographic data, APACHE II, SOFA, reason for MV, comorbidity, functional condition, reintubation, duration of MV, tracheotomy, ICU mortality, in-hospital mortality.ResultsA total of 1661 patients were recruited. Males accounted for 67.9% (n=1127), with a mean age of 62.1 ± 16.2 years. APACHE II: 20.3 ± 7.5. Total SOFA: 8.4 ± 3.5. Four hundred and twenty-three patients (25.4%) were ≥ 75 years of age. Comorbidity and functional condition rates were poorer in these patients (p<0.001 for both variables). Mortality in the ICU was higher in the elderly patients (33.6%) than in the younger subjects (25.9%) (p=0.002). Also, in-hospital mortality was higher in those ≥ 75 years of age. No differences in duration of MV, prevalence of tracheostomy or reintubation incidence were found. Regarding the indication for MV, only the patient ≥ 75 years of age with pneumonia, sepsis or trauma had a higher in-ICU mortality than the younger patients (46.3% vs 33.1%, p=0.006; 55% vs 25.8%, p=0.002; 63.6% vs 4.5%, p<0,001, respectively). No differences were found referred to other reasons for MV.ConclusionOlder patients (≥ 75 years) have significantly higher in-ICU and in-hospital mortality than younger patients without differences in the duration of mechanical ventilation. Differences in mortality were at the expense of pneumonia, sepsis and trauma.Copyright © 2012 Elsevier España, S.L. and SEMICYUC. All rights reserved.

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