• Russell Portenoy.
• Beth Israel Medical Center, First Avenue at 16th Street, New York, NY 10003, USA. rportenoy@chpnet.org
• Curr Med Res Opin. 2006 Aug 1;22(8):1555-65.

ObjectiveTo develop a patient-completed screening tool to help differentiate nociceptive and neuropathic pain.Research Design And MethodsA multicenter study was performed for item reduction (initial 89-item questionnaire) and model building. Patients (N = 586) with non-headache chronic pain completed the questionnaire and were referred to pain specialists for diagnosis. Factor and regression analyses were used to derive a final, 6-item questionnaire--ID Pain. A second multicenter study evaluated reliability and validity. Patients (N = 308) treated by pain specialists completed ID Pain and validation measures.Main Outcome MeasuresSensitivity and specificity were assessed using receiver operating characteristic curves and the concordance c index. Reliability was assessed using a kappa statistic and intraclass correlation coefficient.ResultsFinal 6 items were: did the pain feel: (1) like pins and needles? (2) hot/burning? (3) numb? (4) like electrical shocks? (5) is the pain made worse with the touch of clothing or bed sheets? (6) is the pain limited to your joints? "Yes" answers to questions 1-5 were scored as 1, while a "yes" answer to question 6 was scored as -1. "No" answers were scored as 0. Higher scores (-1 to 5) suggested a neuropathic component. The questionnaire accurately predicted diagnoses of neuropathic pain made by pain specialists. The concordance c indices in the studies were 0.73 and 0.69. The ICC was 0.742; the kappa statistic ranged from 0.742 to 0.527.ConclusionsID Pain appeared to accurately indicate the presence of a neuropathic component of pain. As a brief, self-administered screening tool, it could be useful in primary care settings.

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